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Agenerase and Ziagen

Determining the interaction of Agenerase and Ziagen and the possibility of their joint administration.

Check result:
Agenerase <> Ziagen
Relevance: 05.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Coadministration of amprenavir with abacavir results in increased blood levels of amprenavir. Average amprenavir levels increased 29% in the area under the time concentration curve during concomitant administration. The clinical significance is unknown. Patients receiving this combination should be monitored for altered efficacy and safety.

References
  • "Product Information. Agenerase (amprenavir)." Glaxo Wellcome, Research Triangle Pk, NC.
Agenerase

Generic Name: amprenavir

Brand name:

Synonyms: n.a.

Ziagen

Generic Name: abacavir

Brand name: Ziagen

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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