Agrylin and Phenobarbital Tablets
Determining the interaction of Agrylin and Phenobarbital Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Anagrelide may alter the blood levels and effects of PHENobarbital. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Contact your doctor if you experience increased side effects or your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with inducers of CYP450 1A2 may decrease the plasma concentrations of anagrelide and increase the plasma concentrations of its pharmacologically active metabolite, 3-hydroxy-anagrelide.
MANAGEMENT: Clinical and laboratory monitoring are recommended if anagrelide is used in combination with a CYP450 1A2 inducer. Dose adjustments may also be required.
- Cerner Multum, Inc. "Australian Product Information." O 0
- "Product Information. Agrylin (anagrelide)." Roberts Pharmaceutical Corporation, Eatontown, NJ.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: phenobarbital
Brand name: Solfoton, Luminal
Synonyms: Phenobarbital, PHENobarbital
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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