Akynzeo Intravenous and Rocuronium Bromide Injection

• Generic Name: fosnetupitant / palonosetron
• Dosage Forms: n.a.
• Other Brand Names: Akynzeo for injection

Fosnetupitant and palonosetron combination injection is used together with dexamethasone to prevent nausea and vomiting that is caused by cancer medicines (chemotherapy). Palonosetron and fosnetupitant work by blocking the signals to the brain that cause nausea and vomiting.

This medicine is to be given only by or under the direct supervision of your doctor.

• Generic Name: rocuronium
• Dosage Forms: injection
• Other Brand Names: Zemuron

Production of skeletal muscle relaxation during surgery after general anesthesia has been induced.

Facilitation of endotracheal intubation (rapid sequence and routine tracheal intubation).

Also has been used to facilitate mechanical ventilation in the ICU; however, manufacturer states that prolonged use in this setting has not been evaluated. Whenever neuromuscular blocking agents are used in the ICU, consider benefits versus risks of such therapy and assess patients frequently to determine need for continued paralysis. (See Intensive Care Setting under Cautions.)

Compared with other neuromuscular blocking agents, rocuronium has a rapid onset and intermediate duration of action. Recommended as an alternative to succinylcholine for rapid sequence intubation. When given in sufficient doses (e.g., ≥1 mg/kg), produces similar intubating conditions to succinylcholine.