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Ala-Tet and Fleet (Glycerin Enema)

Determining the interaction of Ala-Tet and Fleet (Glycerin Enema) and the possibility of their joint administration.

Check result:
Ala-Tet <> Fleet (Glycerin Enema)
Relevance: 10.10.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

The coadministration of diuretics and tetracyclines may result in decreased renal function manifested by increases in serum creatinine and blood urea nitrogen (BUN). Usually, no clinical intervention is necessary, unless decreases in renal function occur. If renal function deteriorates, discontinuation of one or both agents may be necessary.

References
  • Garty M, Hurwitz A "Effect of cimetidine and antacids on gastrointestinal absorption of tetracycline." Clin Pharmacol Ther 28 (1980): 203-7
  • Tannenberg AM "Tetracycline and rises in urea nitrogen." JAMA 221 (1972): 713
  • Jick H, Slone D, Shapiro S, et al "Tetracycline and drug-attributed rises in blood urea nitrogen: a report from the Boston Collaborative Drug Surveillance Program." JAMA 220 (1972): 377-9
  • Alexander MR "Tetracycline and rises in urea nitrogen." JAMA 221 (1972): 713-4
Ala-Tet

Generic Name: tetracycline

Brand name: Ala-Tet, Brodspec, Panmycin, Sumycin, Tetracap, Tetracon, Robitet 500, Emtet-500

Synonyms: n.a.

Fleet (Glycerin Enema)

Generic Name: glycerin

Brand name: Fleet Glycerin Suppositories Adult, Fleet Glycerin Suppositories Pediatric, Pedia-Lax Liquid, Sani-Supp, Osmoglyn, Fleet Babylax, Glycerin Suppositories Maximum Strength, Colace Glycerin Suppositories, Tixylix Baby, Glycerol Adult, Senokot Direct Relief, Glycerol, Ichthammol Glycerin, Ravin, Glycerol Infant, Glycerol Pediatric, Boots Cough Syrup 3 Months Plus, Gilseal Homecare Glycerol BP, Allens Junior Cough, Bandi S15, Avedana Glycerin Suppositories Adult

Synonyms: Glycerin (rectal), Glycerin

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction