Alclometasone Dipropionate and Venlafaxine Hydrochloride

• Generic Name: alclometasone topical
• Dosage Forms: n.a.
• Other Brand Names: Aclovate

Relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Generally most effective in acute or chronic dermatoses (e.g., seborrheic or atopic dermatitis, localized neurodermatitis, anogenital pruritus, psoriasis, late phase of allergic contact dermatitis, inflammatory phase of xerosis).

Topical therapy generally preferred over systemic therapy; fewer associated adverse systemic effects.

Topical therapy generally only controls manifestations of dermatoses; eliminate cause if possible.

Topical efficacy may be increased by using a higher concentration or occlusive dressing therapy. (See Administration with Occlusive Dressing under Dosage and Administration.)

Response may vary from one topical corticosteroid preparation to another.

Anti-inflammatory activity may vary considerably depending on the vehicle, drug concentration, site of application, disease, and individual patient.

Manufacturers state that alclometasone should not be used for the treatment of acne, rosacea, or perioral dermatitis.

Alclometasone dipropionate 0.05% cream and ointment are considered to have low-to-medium range potency.

• Generic Name: venlafaxine
• Dosage Forms: n.a.
• Other Brand Names: Effexor XR, Effexor

Management of major depressive disorder.

Efficacy of extended-release capsules in hospital settings not established.

Management of generalized anxiety disorder.

Management of social phobia (social anxiety disorder).

Management of panic disorder with or without agoraphobia.

Not indicated for the management of exogenous obesity (either alone or in combination with weight loss agents such as phentermine), although weight loss reported in some patients receiving the drug for other disorders.

Management of vasomotor symptoms in women with breast cancer and in postmenopausal women; improved both frequency and severity of vasomotor symptoms (hot flushes [flashes]).