Aldesleukin and Omnipaque

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Ask your doctor before using aldesleukin together with iohexol. Iohexol can increase the risk of seizures. Call the doctor if you have side effects such as nausea, vomiting, diarrhea, fever, chills, rash, itiching, low blood pressure, fluid retension. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: Intrathecal administration of iodinated contrast media may induce seizures. There may be a theoretical risk of increased seizure potential when iodinated contrast agents are used with other substances that can reduce the seizure threshold such as aldesleukin.

MONITOR CLOSELY: An increased incidence (12.6%) of acute, atypical reactions to iodinated contrast media has been observed in patients who have been previously treated with interleukin-2. The cause and mechanism have not been established. Symptoms generally have an onset of 1 to 4 hours and may include nausea, vomiting, diarrhea, fever, chills, rash, pruritus, hypotension, edema, and oliguria. Reactions have typically been reported when patients received iodinated contrast media within 4 weeks after the last dose of interleukin-2, but have also occurred several months after interleukin treatment.

MANAGEMENT: Aldesleukin should preferably be withheld for at least 48 hours prior to and 24 hours following intrathecal administration of iodinated contrast media. Patients should be monitored for adverse reactions during and after the myelography, and symptomatic treatment initiated as clinically appropriate.

Aldesleukin

Generic Name: aldesleukin

Brand name: Proleukin

Synonyms: n.a.

What is Aldesleukin?

Omnipaque

Generic Name: iohexol

Brand name: Omnipaque

Synonyms: Iohexol

What is Omnipaque?