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Aldesleukin Intravenous and Diphenhydramine and Phenylephrine Oral Strips

Determining the interaction of Aldesleukin Intravenous and Diphenhydramine and Phenylephrine Oral Strips and the possibility of their joint administration.

Check result:

Aldesleukin Intravenous <> Diphenhydramine and Phenylephrine Oral Strips

Relevance: 26.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using aldesleukin together with diphenhydrAMINE may increase side effects such as drowsiness, depression, confusion and, rarely, coma. Contact your doctor if you experience excessive tiredness or drowsiness during treatment with aldesleukin. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Sedatives, tranquilizers, muscle relaxants, antidepressants, and other central nervous system (CNS) depressants may have additive CNS-depressant effects with aldesleukin. Aldesleukin has been associated with CNS effects including depression, confusion, and drowsiness, which may progress to coma.

MANAGEMENT: Caution is advised if aldesleukin is used with sedatives, hypnotics, tranquilizers, or other CNS-active medications. Patients should be monitored for CNS depression and other CNS adverse effects. Treatment with aldesleukin should be discontinued if severe lethargy or somnolence develop.

References

Agencia Española de Medicamentos y Productos Sanitarios Healthcare "Centro de información online de medicamentos de la AEMPS - CIMA. Available from: URL: https://cima.aemps.es/cima/publico/home.html." ([2018]):
"Product Information. Proleukin (aldesleukin)." Chiron Therapeutics, Emeryville, CA.
Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Aldesleukin Intravenous

Generic Name: aldesleukin

Brand name: Proleukin

Synonyms: Aldesleukin

What is Aldesleukin Intravenous?

Diphenhydramine and Phenylephrine Oral Strips

Generic Name: diphenhydramine / phenylephrine

Brand name: Children's Triacting Night Time, Delsym Children's Night Time Cough & Cold, Dimetapp Nighttime Cold & Congestion, Dytan-D, PediaCare Children's Allergy & Cold, Robitussin Night Time Cough & Cold, Triaminic Night Time Cold & Cough, Diphentann-D, D-Tann, Uni-Tann D, Aldex-CT, Diphenmax D, Alahist LQ, Robitussin Night Time Cough & Cold Pediatric, Robitussin Night Time Cough & Cold Children's, Delsym Children's Nighttime Cough and Cold, Zoden PD, Benadryl-D Children's Allergy & Sinus, Children's Allergy Plus Congestion, PediaCare Children's NightRest, Children's Triaminic Cough/Cold Nighttime, Theraflu Cold/Cough Nighttime

Synonyms: Diphenhydramine and phenylephrine

What is Diphenhydramine and Phenylephrine Oral Strips?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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