Aldesleukin Intravenous and Intron-A (Interferon Alfa-2b Powder for Injection)

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Talk to your doctor before using aldesleukin together with interferon alfa-2b. Combining these medications may increase the risk of serious side effects such as heart attack, inflammation of the heart, other heart problems, and a rare but serious condition called rhabdomyolysis that involves the breakdown of skeletal muscle tissue. In some cases, rhabdomyolysis can cause kidney damage and even death. Let your doctor know immediately if you have unexplained muscle pain, tenderness or weakness, especially if these symptoms are accompanied by fever or dark-colored urine. You should also seek immediate medical attention if you experience chest pain, chest tightness, shortness of breath, difficulty breathing, or irregular heartbeat. Occasionally, using these medications together or one after the other has also been associated with serious allergic reactions. You should be monitored closely by your doctor for signs of a reaction so that emergency treatment may be administered if necessary. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR CLOSELY: The concomitant use of aldesleukin and interferon alfa may increase the risk of severe rhabdomyolysis and myocardial injury, including myocardial infarction, myocarditis and ventricular hypokinesia. In addition, the use of sequential high-dose aldesleukin and interferon alfa has been associated with hypersensitivity reactions requiring medical intervention. Symptoms occurred within a few hours after administration and included erythema, pruritus, and hypotension.

MANAGEMENT: Caution and close clinical and laboratory monitoring for signs and symptoms of toxicity and hypersensitivity reactions is advisable.

Aldesleukin Intravenous

Generic Name: aldesleukin

Brand name: Proleukin

Synonyms: Aldesleukin

What is Aldesleukin Intravenous?

Intron-A (Interferon Alfa-2b Powder for Injection)

Generic Name: interferon alfa-2b

Brand name: Intron A

Synonyms: Intron A

What is Intron-A (Interferon Alfa-2b Powder for Injection)?