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Aldesleukin Intravenous and Kenalog-40

Determining the interaction of Aldesleukin Intravenous and Kenalog-40 and the possibility of their joint administration.

Check result:

Aldesleukin Intravenous <> Kenalog-40

Relevance: 26.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using triamcinolone together with aldesleukin. Triamcinolone may interfere with the effectiveness of aldesleukin in treating your cancer. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Glucocorticoids may antagonize the immunoregulatory properties of aldesleukin and reduce its antitumor effectiveness.

MANAGEMENT: Although glucocorticoids can attenuate aldesleukin-induced side effects including fever, renal insufficiency, hyperbilirubinemia, confusion and dyspnea, concomitant administration of these agents with aldesleukin should generally be avoided. However, patients who develop life-threatening signs or symptoms may be treated with dexamethasone until toxicity resolves to an acceptable level.

References

"Product Information. Proleukin (aldesleukin)." Chiron Therapeutics, Emeryville, CA.

Aldesleukin Intravenous

Generic Name: aldesleukin

Brand name: Proleukin

Synonyms: Aldesleukin

What is Aldesleukin Intravenous?

Kenalog-40

Generic Name: triamcinolone

Brand name: Kenalog-40, Zilretta, Aristocort, Azmacort

Synonyms: Kenalog-40 (injection)

What is Kenalog-40?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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