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Aldesleukin Intravenous and Optiray 160

Determining the interaction of Aldesleukin Intravenous and Optiray 160 and the possibility of their joint administration.

Check result:
Aldesleukin Intravenous <> Optiray 160
Relevance: 26.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using aldesleukin together with ioversol can lead to an increase in side effects. Symptoms generally happen within 1 to 4 hours after the administration of ioversol and may include nausea, vomiting, diarrhea, fever, chills, flu-like symptoms, joint pain, rash, itching, low blood pressure, and swelling. Talk to your doctor before using these medications together. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: An increased incidence (12.6%) of acute, atypical reactions to iodinated contrast media has been observed in patients who have been previously treated with interleukin-2. The cause and mechanism have not been established. Symptoms generally have an onset of 1 to 4 hours and may include nausea, vomiting, diarrhea, fever, chills, flu-like symptoms, joint pain, rash, pruritus, hypotension, edema, and oliguria. Reactions have typically been reported when patients received iodinated contrast media within 4 weeks after the last dose of interleukin-2, but have also occurred several months after interleukin treatment.

MANAGEMENT: Patients should be monitored for adverse reactions after receiving iodinated contrast media, and symptomatic treatment initiated as clinically appropriate.

References
  • "Product Information. Proleukin (aldesleukin)." Chiron Therapeutics, Emeryville, CA.
  • "Product Information. Ultravist (iopromide)." Berlex, Richmond, CA.
Aldesleukin Intravenous

Generic Name: aldesleukin

Brand name: Proleukin

Synonyms: Aldesleukin

Optiray 160

Generic Name: ioversol

Brand name: Optiray 240, Optiray 300, Optiray 320, Optiray 350, Optiray 160

Synonyms: Optiray 160 (Injection)

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction