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Aldex GS DM and Selexipag

Determining the interaction of Aldex GS DM and Selexipag and the possibility of their joint administration.

Check result:

Aldex GS DM <> Selexipag

Relevance: 05.05.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using pseudoephedrine together with selexipag. Using these medications together can make selexipag less effective. You should be counseled to consult with your doctor before taking over-the-counter decongestants. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Concurrent administration of decongestants or vasoconstrictors may negate the vasodilatory effects of prostacyclin analogs in patients with pulmonary hypertension.

MANAGEMENT: The use of decongestants and vasoconstrictors should probably be avoided in patients with pulmonary hypertension. Patients should be counseled to consult with their physician before taking over-the-counter decongestants such as phenylephrine and pseudoephedrine.

References

Hardman JG, Gilman AG, Limbird LE eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 9th ed." New York, NY: McGraw-Hill (1995):
"Product Information. Remodulin (treprostinil)." United Therapeutics Corp, Silver Spring, MD.
"Product Information. Flolan (epoprostenol)." Glaxo Wellcome, Research Triangle Park, NC.

Aldex GS DM

Generic Name: dextromethorphan / guaifenesin / pseudoephedrine

Brand name: Aldex GS DM, Capmist DM, Desgen, Despec-DM, Maxifed DM, Anatuss DM, Ambenyl-D, Dimacol, Novahistine DMX, Ru-Tuss Expectorant, Rhinosyn-X, Sudafed Cough, Dorcol Childrens Cough, Syn-Rx DM, Guaifenex DM RX, Suda-Tussin DM, Pseudogest-DM, Robitussin Pediatric Cough and Decongestant, Benylin Multi-Symptom Cough, Sudafed Cough Syrup, Daytime Liquicap, Multi Symptom Cough and Cold, Tussin Cough and Cold, Protuss DM, Med-RX DM, Tussafed-LA, Touro CC, Balminil DM-D-E Extra Strength, Benylin DM-D-E, Benylin DM-D-E Extra Strength, Calmylin #4, Novahistine DM Expectorant with Decongestant, Medent DM, Robitussin CF, Profen Forte DM, Profen II DM, Profen II DM Liquid, S-Pak DM, Ru-Tuss DM, Dimetapp Cold and Congestion, PanMist-DM, Relacon-DM, Coldmist DM, Z-COF DM, Ambifed-G DM, Tusnel Pediatric, Touro CC-LD, Relacon-DM NR, Despec Drops, Liquicough DM, Pseudo Cough, Relasin DM, Z-Cof 12DM, Q-Tussin CF, Ambi 60/580/30, Ambi 80/780/40, Ambi 600/1000/30, Trikof-D, Pseudo DM GG, Pseudo Max DMX, SudaTex-DM, ExeFen-DMX, Medent-DMI, Donatussin DM Syrup, Ambifed DM, Tenar DM, Robitussin D, ExeClear-DM, Z-Cof 8DM, Robitussin D Cough & Cold, TL-Dex DM, Tusnel DM Pediatric Drops, Trispec PSE, Poly-Vent DM, Tusnel-DM Pediatric Drops

Synonyms: n.a.

What is Aldex GS DM?

Selexipag

Generic Name: selexipag

Brand name: Uptravi, Uptravi Titration Pack

Synonyms: n.a.

What is Selexipag?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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