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Aldomet and Guiatex PE

Determining the interaction of Aldomet and Guiatex PE and the possibility of their joint administration.

Check result:
Aldomet <> Guiatex PE
Relevance: 18.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using phenylephrine together with methyldopa may cause an increase in blood pressure. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or need your blood pressure checked more often to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Limited data suggest that methyldopa and other sympatholytics may increase or prolong the pressor effect of sympathomimetics. Hypertension may result. Data exist for phenylpropanolamine and norepinephrine.

MANAGEMENT: If these drugs must be coadministered, blood pressure should be closely monitored. Discontinuation of the sympathomimetic may be necessary if hypertension develops.

References
  • McLaren EH "Severe hypertension produced by interaction of phenylpropanolamine with methyldopa and oxprenolol." Br Med J 2 (1976): 283-4
  • "Product Information. Allegra-D (fexofenadine-pseudoephedrine)." Chattem Consumer Products, Chattanooga, TN.
Aldomet

Generic Name: methyldopa

Brand name: Aldomet

Synonyms: n.a.

Guiatex PE

Generic Name: guaifenesin / phenylephrine

Brand name: Aldex G, Aquatab D, Deconex, Deconex IR, Donatussin Drops, D-Phen 1000, Duravent PE, Gilphex TR, Liquibid-PD, MucaphEd, Nariz, Prolex D, Sudafed PE Non-Drying Sinus, Supress-PE, Triaminic Chest & Nasal Congestion, Xpect-PE, Sinupan, Deconsal Pediatric, Efasin, Amidal, Chemdal, Quindal, Endal, Liquibid-D, Rescon-GG, SINUvent PE, Entex LA, Entex, Crantex, Crantex LA Capsules, Amitex LA, Entex ER, Duraphen II, Crantex ER, Liquibid-D 1200, Phenavent LA, Phenavent D, Sina-12X, Deconsal II, Guaifed Caps, Guaifed PD, Phenavent, Tussbid, Phenavent PED, Nescon-PD, Pendex, Prolex PD, Aldex, Nasex, Crantex LA Tablets, Duratuss, Duratuss GP, Lusonex, Sitrex, Guaiphen-PD, Wellbid-D, Wellbid-D 1200, Despec, Xedec, Nasex-G, Gentex LA, Guaiphen-D 600, Guaiphen-D 1200, Simuc, Zotex GPX, Duomax, Guaifen PE, Norel EX, Nexphen PD, Respa-PE, Reluri, Duraphen 1000, Dynex LA, Sudex, Extendryl G, Maxiphen, Ambi 40/1000, MontePhen, Xedec II, Simuc-GP, Duratuss PE, Sitrex PD, Refenesen PE, Mydex, Medent-PE, Genexa LA, Nazarin, J-Max, Mucus Relief Sinus, Robitussin Head & Chest Congestion, Visonex, Zyrphen, PE-Guai, Guiadex PD, D-Tab, ExeTuss, ExeTuss-GP, Mucinex Children's Cold, Quintex, Guiatex PE, Fenesin PE IR, Medent-PEI, Liquibid PD-R, Liquibid D-R, Zoden Drops, Entex LQ, Tussi-Pres PE, Lusair, Reese Onetab Congestion & Cough, ED Bron GP, Relcof IR, Giltuss Sinus & Congestion, Zotex-GP

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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