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Aldoril and Pamelor

Determining the interaction of Aldoril and Pamelor and the possibility of their joint administration.

Check result:

Aldoril <> Pamelor

Relevance: 08.12.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Isolated reports have suggested that tricyclic antidepressants may decrease the antihypertensive effect of methyldopa. These reports have not been confirmed by other small studies.

References

White AG "Methyldopa and amitriptyline." Lancet 2 (1965): 441
Reid JL, Porsius AJ, Zamboulis C, Polak G, Hamilton CA, Dean CR "The effects of desmethylimipramine on the pharmacological actions of alpha methyldopa in man." Eur J Clin Pharmacol 16 (1979): 75-80

Aldoril

Generic Name: hydrochlorothiazide / methyldopa

Brand name: Aldoril 15, Aldoril 25, Aldoril D30, Aldoril D50

Synonyms: Aldoril (Oral)

What is Aldoril?

Pamelor

Generic Name: nortriptyline

Brand name: Pamelor, Aventyl, Aventyl HCl

Synonyms: n.a.

What is Pamelor?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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