Alendronate and cholecalciferol and Magnesium citrate
Determining the interaction of Alendronate and cholecalciferol and Magnesium citrate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using cholecalciferol together with magnesium citrate can lead to elevated magnesium blood levels, particularly in individuals with reduced kidney function. Symptoms of high magnesium levels may include nausea, vomiting, flushing, drowsiness, dizziness, confusion, muscle weakness, reduced reflexes, low blood pressure, slow heart rate, and impaired breathing. You should seek medical attention if you experience these symptoms. If you are on dialysis and treated with cholecalciferol or other vitamin D medications, you should generally avoid taking products that contain magnesium without first talking to your doctor, as high levels of magnesium over time can lead to bone problems. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Use of magnesium-containing products with a vitamin D analog may increase the risk of hypermagnesemia, particularly in chronic renal dialysis patients, due to potentially additive pharmacologic effects. Chronic hypermagnesemia may have a role in the pathogenesis of adynamic bone disease in dialysis patients.
MANAGEMENT: Patients on chronic renal dialysis treated with a vitamin D analog should avoid magnesium-containing products.
- "Product Information. Zemplar (paricalcitol)." Abbott Pharmaceutical, Abbott Park, IL.
- "Product Information. Hectorol (doxercalciferol)." Genzyme Corporation, Cambridge, MA.
- "Product Information. One-Alpha (alfacalcidol)." Pharmel Inc, Montreal, IN.
- "Product Information. Rocaltrol (calcitriol)." Roche Laboratories, Nutley, NJ.
Generic Name: alendronate / cholecalciferol
Brand name: Fosamax Plus D
Synonyms: Alendronate and Cholecalciferol
Generic Name: magnesium citrate
Brand name: Citrate of Magnesia, Citroma, Citroma Cherry, Citroma Lemon
Synonyms: Magnesium Citrate
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Alendronate and cholecalciferol-Magnesium Citrate Liquid
- Alendronate and cholecalciferol-Magnesium gluconate
- Alendronate and cholecalciferol-Magnesium hydroxide
- Alendronate and cholecalciferol-Magnesium Hydroxide and Mineral Oil
- Alendronate and cholecalciferol-Magnesium Hydroxide Chewable Tablets
- Alendronate and cholecalciferol-Magnesium Hydroxide Suspension
- Magnesium citrate-Alendronate Effervescent Tablets
- Magnesium citrate-Alendronate Oral Solution
- Magnesium citrate-Alendronate Sodium
- Magnesium citrate-Alendronate Tablets
- Magnesium citrate-Alesse
- Magnesium citrate-Alesse Oral