Alendronate and cholecalciferol and Mineral Oil
Determining the interaction of Alendronate and cholecalciferol and Mineral Oil and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using mineral oil together with cholecalciferol may decrease the effects of cholecalciferol. Cholecalciferol should be administered at least three hours before or after mineral oil. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSING INTERVAL: Coadministration of mineral oil and oral vitamin D (a fat soluble vitamin) may lead to decreased effectiveness of vitamin D. Mineral oil most likely decreases gastrointestinal absorption of vitamin D.
MANAGEMENT: Consider either separating the doses by at least 3 hours, substituting mineral oil with alternative therapy or using parenteral vitamin D.
- "Product Information. Hectorol (doxercalciferol)" Genzyme Corporation, Cambridge, MA.
Generic Name: alendronate / cholecalciferol
Brand name: Fosamax Plus D
Synonyms: Alendronate and Cholecalciferol
Generic Name: mineral oil
Brand name: Fleet Mineral Oil Enema, Kondremul Plain, Muri-Lube, Milkinol, Mineral Oil, Light, Heavy, Liqui Doss, Leader Mineral Oil Enema, Kondremul
Synonyms: Mineral oil (oral/rectal)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Alendronate and cholecalciferol-Mineral Oil Enema
- Alendronate and cholecalciferol-Mineral Oil Oral Emulsion
- Alendronate and cholecalciferol-Mineral Oil Oral Liquid
- Alendronate and cholecalciferol-Mineral oil oral/rectal
- Alendronate and cholecalciferol-Minerals with Vitamins
- Alendronate and cholecalciferol-Mini-Prenatal
- Mineral Oil-Alendronate Effervescent Tablets
- Mineral Oil-Alendronate Oral Solution
- Mineral Oil-Alendronate Sodium
- Mineral Oil-Alendronate Tablets
- Mineral Oil-Alesse
- Mineral Oil-Alesse Oral