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Alendronate and cholecalciferol and Natpara

Determining the interaction of Alendronate and cholecalciferol and Natpara and the possibility of their joint administration.

Check result:
Alendronate and cholecalciferol <> Natpara
Relevance: 02.11.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Alendronate may reduce the effectiveness of parathyroid hormone in normalizing your calcium levels. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: Alendronate may reduce the therapeutic effects of parathyroid hormone. Coadministration of alendronate and parathyroid hormone leads to reduction in the calcium-sparing effect, which can interfere with the normalization of serum calcium.

MANAGEMENT: Concomitant use of parathyroid hormone with alendronate is not recommended.

References
  • "Product Information. Natpara (parathyroid hormone)." NPS Pharmaceuticals, Bedminster, NJ.
Alendronate and cholecalciferol

Generic Name: alendronate / cholecalciferol

Brand name: Fosamax Plus D

Synonyms: Alendronate and Cholecalciferol

Natpara

Generic Name: parathyroid hormone

Brand name: Natpara

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle