Alendronate and cholecalciferol and Polysaccharide-Iron Complex Capsules and Tablets
Determining the interaction of Alendronate and cholecalciferol and Polysaccharide-Iron Complex Capsules and Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Alendronate and iron polysaccharide should not be taken orally at the same time. Products that contain magnesium, aluminum, calcium, iron, and/or other minerals may interfere with the absorption of alendronate into the bloodstream and reduce its effectiveness. You should take iron polysaccharide at least 30 minutes after the alendronate dose. Talk to a healthcare professional if you are not sure whether a product contains something that could potentially interact with your medication or if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSING INTERVAL: Products containing aluminum, calcium, magnesium and other polyvalent cations such as antacids or vitamin with mineral supplements are likely to interfere with the gastrointestinal absorption of oral bisphosphonates. For example, the bioavailability of tiludronate has been shown to decrease 80% during simultaneous administration with calcium, and 60% when aluminum- or magnesium-containing antacids were administered one hour before tiludronate.
MANAGEMENT: Antacids or other oral medications containing aluminum, calcium, magnesium and other polyvalent cations should be administered at least 30 minutes after the bisphosphonate dose.
- Darcy PF "Nutrient-drug interactions." Adverse Drug React Toxicol Rev 14 (1995): 233-54
- "Product Information. Boniva (ibandronate)." Roche Laboratories, Nutley, NJ.
- "Product Information. Skelid (tilundronate)." Sanofi Winthrop Pharmaceuticals, New York, NY.
- "Product Information. Bonefos (clodronate)." Rhone-Poulenc Rorer Canada Inc, Laval, QC.
- "Product Information. Actonel (risedronate)." Procter and Gamble Pharmaceuticals, Cincinnati, OH.
- "Product Information. Fosamax (alendronate)." Merck & Co, Inc, West Point, PA.
Generic Name: alendronate / cholecalciferol
Brand name: Fosamax Plus D
Synonyms: Alendronate and Cholecalciferol
Generic Name: iron polysaccharide
Brand name: Ezfe, Ferrex-150, Ferus Pic-150, Iferex 150, Niferex Elixir, NovaFerrum 50, Nu-Iron 150, Poly Iron, ProFe, Myferon 150, Novaferrum, Poly-Iron, Fe-Tinic 150, Ferrex 150 Plus, Niferex-150
Synonyms: Iron polysaccharide
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Alendronate and cholecalciferol-Polysaccharide-Iron Complex Liquid
- Alendronate and cholecalciferol-Polysaccharide-Iron Complex, Vitamin B12, and Folic Acid
- Alendronate and cholecalciferol-Polyvitamin Drops with Iron
- Alendronate and cholecalciferol-Polyvitamin OR SOLN
- Alendronate and cholecalciferol-Pomalidomide
- Alendronate and cholecalciferol-Pomalyst
- Polysaccharide-Iron Complex Capsules and Tablets-Alendronate Effervescent Tablets
- Polysaccharide-Iron Complex Capsules and Tablets-Alendronate Oral Solution
- Polysaccharide-Iron Complex Capsules and Tablets-Alendronate Sodium
- Polysaccharide-Iron Complex Capsules and Tablets-Alendronate Tablets
- Polysaccharide-Iron Complex Capsules and Tablets-Alesse
- Polysaccharide-Iron Complex Capsules and Tablets-Alesse Oral