Aleve Cold and Sinus and Diclofenac Topical Solution
Determining the interaction of Aleve Cold and Sinus and Diclofenac Topical Solution and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Talk to your doctor before using diclofenac topical together with naproxen. Both of these medications are considered nonsteroidal anti-inflammatory drugs. Since the medication in diclofenac topical may be absorbed from the skin, combining it with naproxen may increase the risk and/or severity of side effects reported with this class of drugs, including stomach ulcer, fluid retention, high blood pressure, bleeding, and liver or kidney problems. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Nonsteroidal anti-inflammatory drugs may be absorbed systemically following topical administration. Concomitant use with systemic nonsteroidal anti-inflammatory drugs may result in increased adverse effects such as gastrointestinal toxicity (inflammation, bleeding, ulceration, perforation), cardiovascular thrombotic events, hepatotoxicity (liver enzyme elevations), renal toxicity, fluid retention, edema, hypertension, and inhibition of platelet aggregation.
MANAGEMENT: Patients treated with topical preparations of nonsteroidal anti-inflammatory drugs should avoid or limit the use of systemic nonsteroidal anti-inflammatory drugs. Although systemic exposure is generally low following topical administration, absorption may be increased with frequent applications; use of large quantities or over large areas of skin; use on compromised or diseased skin or open wounds; and use of occlusive dressings or heating pads over application areas.
- "Product Information. Solaraze (diclofenac topical)." Doak Dermatologics Division, Fairfield, NJ.
Generic Name: naproxen / pseudoephedrine
Brand name: Aleve Cold and Sinus, Aleve Sinus & Headache, Aleve-D Sinus & Cold, Sudafed PSE, Aleve-D Cold and Sinus, Sudafed Sinus & Pain 12 Hour, Sinus & Cold-D, Sudafed Sinus 12 Hour Pressure + Pain, Aleve-D Sinus & Headache, Sudafed 12 Hour Pressure + Pain
Synonyms: n.a.
Generic Name: diclofenac topical
Brand name: DST Plus Pak, Pennsaid, Solaraze, Voltaren Topical, Diclozor, Voltaren, Flector Patch, Klofensaid II, Vopac MDS, Xrylix, Flector, Licart
Synonyms: Diclofenac topical, Diclofenac (Topical)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Aleve Cold and Sinus-Diclofenac transdermal
- Aleve Cold and Sinus-Diclofex DC
- Aleve Cold and Sinus-Diclosiacin
- Aleve Cold and Sinus-Dicloxacillin
- Aleve Cold and Sinus-Dicloxacillin Sodium
- Aleve Cold and Sinus-Diclozor
- Diclofenac Topical Solution-Aleve PM
- Diclofenac Topical Solution-Aleve Sinus & Headache
- Diclofenac Topical Solution-Aleve-D Sinus & Cold
- Diclofenac Topical Solution-Aleve-D Sinus & Headache
- Diclofenac Topical Solution-Aleveer Patch
- Diclofenac Topical Solution-Alfenta