Alfentanil Intravenous and Codeine, phenylephrine, and promethazine
Determining the interaction of Alfentanil Intravenous and Codeine, phenylephrine, and promethazine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using codeine together with alfentanil may affect your heart and alter your breathing. This can cause changes in blood pressure, arrhythmias, or other heart abnormalities. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSE: Potent narcotics, when used as an adjuvant in patients receiving alfentanil, remifentanil, or sufentanil for anesthesia or conscious sedation, may further decrease cardiac output and respiratory drive.
MANAGEMENT: The dosage of alfentanil, remifentanil, or sufentanil may need to be decreased in patients who have received large doses of narcotics.
- Gilman AG, Rall TW, Nies AS, Taylor P, eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 8th ed." New York, NY: Pergamon Press Inc. (1990):
Generic Name: alfentanil
Brand name:
Synonyms: Alfentanil (Intravenous)
Generic Name: codeine / phenylephrine / promethazine
Brand name: Promethazine VC with Codeine, Phenergan VC with Codeine, M-Phen
Synonyms: Promethazine, Phenylephrine, and Codeine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Alfentanil Intravenous-Codeine, phenylephrine, and triprolidine
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- Alfentanil Intravenous-Coditussin AC
- Codeine, phenylephrine, and promethazine-Alferon N
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- Codeine, phenylephrine, and promethazine-Aliclen Shampoo