Aliskiren Tablets and Lasix Injection

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using furosemide together with aliskiren can decrease the effects of furosemide. Contact your doctor if your condition worsens. You may need a dose adjustment or special tests if your use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Coadministration with aliskiren may decrease the blood concentrations of furosemide. The mechanism of interaction has not been described. According to the product labeling for aliskiren, peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) of furosemide were reduced by approximately 50% and 30%, respectively, during concomitant administration. Furosemide had no significant effect on the systemic exposure of aliskiren.

MANAGEMENT: The potential for diminished pharmacologic effects of furosemide should be considered during coadministration with aliskiren.

Aliskiren Tablets

Generic Name: aliskiren

Brand name: Tekturna

Synonyms: Aliskiren

What is Aliskiren Tablets?

Lasix Injection

Generic Name: furosemide

Brand name: Lasix, Diaqua-2, Lo-Aqua

Synonyms: Lasix

What is Lasix Injection?