Alka-Seltzer Plus-D Sinus/Cold and Tegretol

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using acetaminophen together with carBAMazepine may alter the effects of acetaminophen and cause serious side effects that may affect your liver. Call your doctor immediately if you experience a fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, or yellowing of the skin or the whites of your eyes. If your doctor does prescribe these medications together, you may need a dose adjustment or special tests to safely take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Limited data suggest that carbamazepine may increase the potential hepatotoxicity of acetaminophen and decrease its pharmacologic effects. The mechanism may be related to accelerated CYP450 metabolism of acetaminophen with consequent increase of hepatotoxic metabolites. This interaction is of greatest concern in cases of acetaminophen overdose.

MANAGEMENT: Until more information is available, the use of this combination over a prolonged period of time should probably be avoided. Monitoring for clinical and laboratory evidence of hepatotoxicity is recommended.

Alka-Seltzer Plus-D Sinus/Cold

Generic Name: acetaminophen / chlorpheniramine / dextromethorphan / pseudoephedrine

Brand name: Alka-Seltzer Plus-D Sinus/Cold, Cold Symptoms Relief Maximum Strength, EQ Cold Relief Complete, EQ Cold/Cough Plus, EQL Pain Relief/Cold, Tylenol Cold and Flu Powder, Theraflu Flu, Cold and Cough Powder, Theraflu Nightime Maximum Strength, Comtrex Day and Night, Theraflu Night Cough and Cold and Flu, Co-Apap, Vicks Formula 44M, Cough Formula M Multi-Symptom, Mapap Cold, Child Tylenol Cold Multi-Symptom Plus Cough, Comtrex Cold and Flu Maximum Strength Liquid, Genacol Maximum Strength, Robitussin Honey Flu Nighttime, Children's Tylenol Flu, Alka-Seltzer Plus Cough and Cold Liquigel, Tylenol Cold Complete Formula, Children's Tylenol Cold Plus Cough, Contac Cold and Flu Maximum Strength, Triaminic Flu, Cough & Fever, Theraflu Cold & Cough, Theraflu Severe Cold & Congestion, Theraflu Flu & Cough, Tylenol Cold Day/Night Convenience Pack, Children’s Non-Aspirin Cold/Cough, EQL Pain Relief Plus Cold/Cough, Tylenol Children’s Cold/Cough

Synonyms: n.a.

What is Alka-Seltzer Plus-D Sinus/Cold?

Tegretol

Generic Name: carbamazepine

Brand name: Carbatrol, Epitol, Equetro, Tegretol, Tegretol XR, Tegretol, Tegretol XR

Synonyms: n.a.

What is Tegretol?