Alkeran (Melphalan Tablets) and Cimetidine Sodium Chloride
Determining the interaction of Alkeran (Melphalan Tablets) and Cimetidine Sodium Chloride and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:The oral absorption of melphalan may be reduced by concomitant use of cimetidine. The clinical significance of this interaction is unknown.
- Sviland L, Robinson A, Proctor SJ, Bateman DN "Interaction of cimetidine with oral melphalen: a pharmacokinetic study." Cancer Chemother Pharmacol 20 (1987): 173-5
Generic Name: melphalan
Brand name: Alkeran, Alkeran IV, Evomela
Synonyms: Alkeran (Injection), ALKERAN
Generic Name: cimetidine
Brand name: Tagamet HB, Tagamet
Synonyms: Cimetidine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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