Alkeran (Melphalan Tablets) and Dihydroergotamine Mesylate

• Generic Name: melphalan
• Dosage Forms: n.a.
• Other Brand Names: Alkeran, Alkeran IV, Evomela

• It is used to treat multiple myeloma.
• It is used to treat cancer of the ovary.
• It may be given to you for other reasons. Talk with the doctor.

• Generic Name: dihydroergotamine
• Dosage Forms: n.a.
• Other Brand Names: DHE. 45, Migranal

Acute treatment of migraine attacks (with or without aura) or cluster headaches.

One of several preferred initial therapies in moderate to severe migraines or mild to moderate migraines that respond poorly to NSAIAs.

IV treatment of intractable migraines (e.g., status migrainosus); usually used in combination with IV antiemetic.

Not recommended for management of hemiplegic or basilar migraine or for prophylaxis or chronic daily management of migraine.

Used in combination with low-dose heparin therapy for prevention of postoperative DVT and pulmonary embolism; generally has been replaced by other more effective therapies (e.g., low molecular weight heparin alone, warfarin).