Alli and Ospemifene

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Orlistat may reduce the blood levels and effects of ospemifene. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Let your doctor know if ospemifene becomes less effective or is no longer controlling your symptoms. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Coadministration of orlistat with ospemifene may result in a reduction in the bioavailability and therapeutic effects of ospemifene. By partially inhibiting the absorption of dietary fat, orlistat may indirectly reduce the gastrointestinal absorption of ospemifene, which is lipophilic in nature.

MANAGEMENT: Caution is advised if orlistat and ospemifene are used in combination. Patients should be monitored for clinical evidence of altered ospemifene efficacy. Separating the doses of orlistat and ospemifene by at least 2 hours may help minimize the potential for an interaction.

Alli

Generic Name: orlistat

Brand name: Alli, Xenical, Alli

Synonyms: alli

What is Alli?

Ospemifene

Generic Name: ospemifene

Brand name: Osphena

Synonyms: n.a.

What is Ospemifene?