Allopurinol and lesinurad and St. Joseph 81 mg Adult
Determining the interaction of Allopurinol and lesinurad and St. Joseph 81 mg Adult and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Depending on the dose, aspirin may reduce the effectiveness of lesinurad. If you are taking low doses of aspirin (e.G., 325 mg per day or less) to prevent heart attack or stroke, you may continue to do so while receiving lesinurad. However, higher doses of aspirin such as those used for pain or fever may interfere with the effects of lesinurad. Talk to a healthcare provider if you have any questions or concerns. Your doctor or pharmacist may be able to recommend alternatives that do not interact with lesinurad. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: According to the product labeling for lesinurad, aspirin at dosages higher than 325 mg/day may reduce the efficacy of lesinurad in combination with allopurinol. The mechanism of interaction has not been described.
MANAGEMENT: The potential for diminished therapeutic effects of lesinurad should be considered when coadministered with aspirin at dosages higher than 325 mg/day. Alternative treatments may be required if an interaction is suspected. Aspirin at dosages of 325 mg/day or less given for cardiovascular protection does not decrease the efficacy of lesinurad based on data from premarketing clinical studies.
- "Product Information. Zurampic (lesinurad)." Astra-Zeneca Pharmaceuticals, Wilmington, DE.
Generic Name: allopurinol / lesinurad
Brand name: Duzallo
Synonyms: Lesinurad and Allopurinol
Generic Name: aspirin
Brand name: Bayer Children's, St. Joseph 81 mg Adult, Arthritis Pain, Aspir 81, Aspir-Low, Bayer Childrens Aspirin, Durlaza, Ecotrin, Ecpirin, Fasprin, Halfprin, Miniprin, Aspiritab, Bayer, Bayer Low Strength
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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