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Allopurinol Injection and Gaviscon

Determining the interaction of Allopurinol Injection and Gaviscon and the possibility of their joint administration.

Check result:
Allopurinol Injection <> Gaviscon
Relevance: 22.03.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using aluminum hydroxide together with allopurinol may decrease the effects of allopurinol. Allopurinol should be administered at least one hour before or two hours after aluminum hydroxide. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Aluminum-containing oral medications may decrease the absorption of allopurinol and reduce its therapeutic effect.

MANAGEMENT: Allopurinol should be administered at least one hour before or two hours after aluminum-containing medications.

References
  • Weissman I, Krivoy N "Interaction of aluminum hydroxide and allopurinol in patients on chronic hemodialysis." Ann Intern Med 107 (1987): 787
Allopurinol Injection

Generic Name: allopurinol

Brand name: Zyloprim, Lopurin, Aloprim

Synonyms: Allopurinol

Gaviscon

Generic Name: aluminum hydroxide / magnesium carbonate

Brand name: Acid Gone, Gaviscon, Gaviscon Extra Relief Formula

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction