Allopurinol Intravenous and Entecavir Oral Solution
Determining the interaction of Allopurinol Intravenous and Entecavir Oral Solution and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using entecavir together with allopurinol may increase the blood levels of one or both medications. Contact your doctor if your condition changes or you experience increased side effects. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration of entecavir with another drug that is also eliminated by active tubular secretion may result in increased plasma concentrations of one or both drugs due to competitive inhibition of transporters in the renal tubules. Drugs (and/or their metabolites) that are thought to undergo active tubular secretion include acyclovir, allopurinol, aminosalicylic acid, cidofovir, cimetidine, creatine, dyphylline, famciclovir, famotidine, flecainide, ganciclovir, levetiracetam, metformin, methotrexate, midodrine, mycophenolic acid, oseltamivir, pralatrexate, probenecid, procainamide, quinidine, ranitidine, tenofovir, triamterene, trimethoprim, valacyclovir, valganciclovir, zalcitabine, zidovudine, and many of the beta-lactam and quinolone antibiotics.
MANAGEMENT: Patients receiving entecavir with another drug that undergoes active tubular secretion should be monitored for excessive pharmacologic effects of both drugs, and the dosages adjusted as necessary.
- "Product Information. Baraclude (entecavir)." Bristol-Myers Squibb, Princeton, NJ.
Generic Name: allopurinol
Brand name: Zyloprim, Lopurin, Aloprim
Synonyms: Allopurinol
Generic Name: entecavir
Brand name: Baraclude
Synonyms: Entecavir
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Allopurinol Intravenous-Entecavir Tablets
- Allopurinol Intravenous-Entercote
- Allopurinol Intravenous-Entereg
- Allopurinol Intravenous-Entex
- Allopurinol Intravenous-Entex HC
- Allopurinol Intravenous-Entex PSE
- Entecavir Oral Solution-Allopurinol Tablets
- Entecavir Oral Solution-Allzital
- Entecavir Oral Solution-Almacone
- Entecavir Oral Solution-Almotriptan
- Entecavir Oral Solution-Almotriptan Malate
- Entecavir Oral Solution-Alodox