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Almacone and Chenodiol

Determining the interaction of Almacone and Chenodiol and the possibility of their joint administration.

Check result:
Almacone <> Chenodiol
Relevance: 04.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Talk to your doctor before using chenodeoxycholic acid together with aluminum hydroxide. Products that contain aluminum may interfere with the absorption of chenodeoxycholic acid and reduce its effectiveness. It may be possible to prevent or minimize the interaction by separating the dosing times by several hours. However, your doctor may be able to suggest safer alternatives to aluminum hydroxide while you are being treated with chenodeoxycholic acid. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Aluminum-based antacids have been shown to adsorb bile acids in vitro and may be expected to interfere with the gastrointestinal absorption of chenodeoxycholic acid, which is a naturally occurring human bile acid.

MANAGEMENT: To minimize the potential for interaction, it may be helpful to separate the dosing of chenodeoxycholic acid and aluminum-based antacids by several hours. However, clinical data are lacking to support a recommendation.

References
  • "Product Information. Chenodal (chenodeoxycholic acid)." Manchester Pharmaceutical, Fort Collins, CO.
Almacone

Generic Name: aluminum hydroxide / magnesium hydroxide / simethicone

Brand name: Almacone, Gelusil, Mag-al Plus, Mi-Acid, Milantex, Mintox, Mylanta Maximum Strength, Rulox, Mylanta Fast Acting, Mylanta DS Fast Acting, Maalox Plus, Masanti DS, Masanti II, Masanti, Alamag Plus, Mi-Acid II, Almacone-2, Mintox Plus, Mylagen, Mylagen-II, Magaant, Ri-Mox Plus, Rulox Plus, Di-Gel, Ri-Gel II, Uni-Lan, Uni-Lan II, Urban, Urban DS, Maldroxal Plus, Maalox Plus Extra Strength, Tempo, Mylanta, Maalox Max, Maalox, Aldroxicon I, Aldroxicon II, Maalox Antacid Antigas Regular Strength, Mintox Extra Strength, Mintox Maximum Strength, Comfort Gel Original, Comfort Gel Extra Strength, Mylanta Maximum Strength Cherry, Maalox Max Wild Berry, Maalox Advanced Maximum Strength, Milantex Maximum Strength, Maalox Advanced Regular Strength, Geri-Lanta, Mag-al Plus XS, Mylanta Maximum Strength Vanilla Caramel, Mi-Acid Maximum Strength, Di-Gel Liquid

Synonyms: n.a.

Chenodiol

Generic Name: chenodeoxycholic acid

Brand name: Chenodal

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction