Alogliptin and pioglitazone and PCE Dispertab

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using erythromycin together with pioglitazone can increase the effects of pioglitazone, which can lead to hypoglycemia (low blood sugar). This can cause headache, dizziness, drowsiness, nausea, hunger, tremor, weakness, sweating, and palpitations. Talk with your doctor before using erythromycin while you are using pioglitazone. You may need a dose adjustment and you may need to check your blood sugar more often. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Pioglitazone is metabolized by CYP450 3A4 microsomal enzymes in the liver. The clinician should be aware of the potential for an interaction when pioglitazone is used in combination with another medication that inhibits and is also metabolized by CYP450 3A4.

MANAGEMENT: Monitoring for clinical and laboratory evidence of altered safety and efficacy of both drugs if pioglitazone is added to or removed from the patients medication regimen is recommended. Patients should be advised to regularly monitor their blood sugar, counseled on how to recognize and treat hypoglycemia (e.g., headache, dizziness, drowsiness, nausea, tremor, hunger, weakness, or palpitations) and to notify their physician if it occurs.

Alogliptin and pioglitazone

Generic Name: alogliptin / pioglitazone

Brand name: Oseni

Synonyms: Alogliptin and Pioglitazone

What is Alogliptin and pioglitazone?

PCE Dispertab

Generic Name: erythromycin

Brand name: EES. Granules, EES-400 Filmtab, EryPed 200, EryPed 400, Ery-Tab, Erythrocin Lactobionate, Erythrocin Stearate Filmtab, PCE Dispertab, E. E. S, EryPed, Erythrocin, Erythromycin Filmtabs, Erythromycin Lactobionate - IV

Synonyms: PCE Dispertab (Oral), PCE, PCE (Oral)

What is PCE Dispertab?