Alogliptin and Pioglitazone Tablets and Nifedical XL
Determining the interaction of Alogliptin and Pioglitazone Tablets and Nifedical XL and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:According to the pioglitazone labeling, coadministration of pioglitazone for 7 days with extended-release nifedipine 30 mg (brand not specified) orally once daily for 4 days to male and female volunteers resulted in slightly decreased bioavailability of nifedipine. The clinical significance of this finding is unknown. However, given the high variability of nifedipine pharmacokinetics, it may be appropriate to monitor patients for potentially diminished therapeutic effects of nifedipine when given with pioglitazone.
- "Product Information. Actos (pioglitazone)" Takeda Pharmaceuticals America, Lincolnshire, IL.
Generic Name: alogliptin / pioglitazone
Brand name: Oseni
Synonyms: Alogliptin and pioglitazone, Alogliptin and Pioglitazone
Generic Name: nifedipine
Brand name: Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia, Procardia XL, Adalat
Synonyms: Nifedical XL (Oral)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Alogliptin and Pioglitazone Tablets-Nifedipine
- Alogliptin and Pioglitazone Tablets-Nifedipine Capsules
- Alogliptin and Pioglitazone Tablets-Nifedipine Extended-Release Tablets
- Alogliptin and Pioglitazone Tablets-Niferex
- Alogliptin and Pioglitazone Tablets-Niferex Elixir
- Alogliptin and Pioglitazone Tablets-Night Cast R Topical
- Nifedical XL-Alogliptin Benzoate
- Nifedical XL-Aloprim
- Nifedical XL-Aloquin
- Nifedical XL-Aloquin Gel
- Nifedical XL-Alora
- Nifedical XL-Alora Transdermal