Alogliptin Benzoate and Inulin Intravenous

• Generic Name: alogliptin
• Dosage Forms: n.a.
• Other Brand Names: Nesina

Used as monotherapy as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus.

Used in combination with pioglitazone (given separately or as the fixed combination) as initial therapy as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus when treatment with both alogliptin and pioglitazone is appropriate.

Used in combination with metformin (given separately or as the fixed combination) as initialtherapy as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus when treatment with both alogliptin and metformin is appropriate.

Used in combination with other oral antidiabetic agents (e.g., metformin, a sulfonylurea, a thiazolidinedione [peroxisome proliferator-activated receptor-γ agonist]) or insulin as an adjunct to diet and exercise in patients with type 2 diabetes mellitus who have not achieved adequate glycemic control.

American Association of Clinical Endocrinologists/American College of Endocrinology (AACE/ACE) suggests a DPP-4 inhibitor as one of several alternatives for initial monotherapy in patients with metformin contraindications (e.g., renal disease, hepatic disease, GI intolerance, risk of lactic acidosis). DPP-4 inhibitors also recommended as part of combination therapy, particularly when both postprandial and fasting plasma glucose concentrations are elevated.

Not indicated for use in patients with type 1 diabetes mellitus or diabetic ketoacidosis.

• Generic Name: inulin
• Dosage Forms: n.a.
• Other Brand Names:

Inulin is used as a test to help diagnose problems or disease of the kidneys. This test determines how well your kidneys are working.

Inulin passes out of the body entirely in the urine. Measuring the amount of inulin in the blood after it has been given can help the doctor determine if the kidneys are working properly.

How test is done:

Inulin is given through an intravenous infusion (run into a vein). The dose of inulin will be different for different patients. The doctor will determine your dose according to your weight and size. Several times during the test, blood and sometimes urine samples are taken. A tube called a catheter may be placed in your bladder to help take the urine samples. The amount of inulin in your blood or urine is measured. Then the results of the test are studied.

Inulin is to be used only under the supervision of a doctor.