Alosetron Hydrochloride and Dantrium (Dantrolene Capsules)

• Generic Name: alosetron
• Dosage Forms: n.a.
• Other Brand Names: Lotronex

Only for management of severe diarrhea-predominant IBS in women with chronic symptoms (generally lasting ≥6 months) who have had anatomic or biochemical GI abnormalities excluded and have not responded to conventional therapy. Diarrhea-predominant IBS is considered severe if accompanied by at least one of the following symptoms: frequent and severe abdominal pain and/or discomfort; frequent bowel urgency or fecal incontinence; or disability or restriction of daily activities.

Use restricted to patients for whom benefit-to-risk balance is considered to be most favorable. (See Boxed Warning.)

Efficacy in men not adequately demonstrated in clinical studies.

• Generic Name: dantrolene
• Dosage Forms: capsule
• Other Brand Names: Dantrium, Dantrium Intravenous, Revonto, Ryanodex

• It is used to relax muscles.
• It is used to treat or prevent a health problem called malignant hyperthermia.