Alosetron Hydrochloride and Diphenoxylate and Atropine Oral Solution

• Generic Name: alosetron
• Dosage Forms: n.a.
• Other Brand Names: Lotronex

Only for management of severe diarrhea-predominant IBS in women with chronic symptoms (generally lasting ≥6 months) who have had anatomic or biochemical GI abnormalities excluded and have not responded to conventional therapy. Diarrhea-predominant IBS is considered severe if accompanied by at least one of the following symptoms: frequent and severe abdominal pain and/or discomfort; frequent bowel urgency or fecal incontinence; or disability or restriction of daily activities.

Use restricted to patients for whom benefit-to-risk balance is considered to be most favorable. (See Boxed Warning.)

Efficacy in men not adequately demonstrated in clinical studies.

• Generic Name: atropine / diphenoxylate
• Dosage Forms: oral solution
• Other Brand Names: Lomotil, Lonox, Lomocot, Vi-Atro

Atropine affects the body in many different ways, such as reducing spasms in the bladder, stomach, and intestines.

Diphenoxylate is an antidiarrheal medication.

Atropine and diphenoxylate is a combination medicine used to treat diarrhea in adults and children who are at least 13 years old.

Atropine and diphenoxylate may also be used for purposes not listed in this medication guide.