Alosetron Hydrochloride and Gammagard

• Generic Name: alosetron
• Dosage Forms: n.a.
• Other Brand Names: Lotronex

Only for management of severe diarrhea-predominant IBS in women with chronic symptoms (generally lasting ≥6 months) who have had anatomic or biochemical GI abnormalities excluded and have not responded to conventional therapy. Diarrhea-predominant IBS is considered severe if accompanied by at least one of the following symptoms: frequent and severe abdominal pain and/or discomfort; frequent bowel urgency or fecal incontinence; or disability or restriction of daily activities.

Use restricted to patients for whom benefit-to-risk balance is considered to be most favorable. (See Boxed Warning.)

Efficacy in men not adequately demonstrated in clinical studies.

• Generic Name: immune globulin intravenous and subcutaneous
• Dosage Forms: injection, solution
• Other Brand Names: Gammagard, Gammaked, Gamunex-C, Gammagard Liquid

Gammagard (immune globulin) is a sterilized solution made from human plasma. It contains the antibodies to help your body protect itself against infection from various diseases.

Gammagard is used to treat primary immunodeficiency diseases (PI) in adults and children two years of age or older.

Gammagard is also used as maintenance therapy to improve muscle strength and disability in adult patients with multifocal motor neuropathy (MMN. MMN is a rare disease that causes muscle weakness that worsens over time. It affects the strength of the lower parts of arms and hands more than the legs, usually without affecting the touch sensation.

There are many forms of PI. The most common types of PI result in an inability to make a very important type of protein called antibodies, which help the body fight off infections from bacteria or viruses.

Gammagard is made from human plasma that is donated by healthy people. It contains antibodies collected from these healthy people that replace the missing antibodies in PI patients.