Alpha Lipoic Acid and Dextran 40

• Generic Name: alpha-lipoic acid
• Dosage Forms: n.a.
• Other Brand Names: Alpha Lipoic Acid, Alpha-Lipoic-Acid-300, Alpha Lipoic

Alpha-lipoic acid is an antioxidant also known as Acetate Replacing Factor, ALA, Biletan, Lipoicin, Thioctan, and many other names.

Alpha-lipoic acid is a naturally occurring fatty acid that can be found in many foods such as yeast, spinach, broccoli, potatoes, and organ meats such as liver or kidney.

Alpha-lipoic acid has been used in alternative medicine as a possibly effective aid in weight loss, treating diabetic nerve pain, healing wounds, lowering blood sugar, improving skin discoloration caused by vitiligo, and decreasing complications of coronary artery bypass graft (CABG) surgery. Alpha-lipoic acid may have been combined with other plants or extracts in a specific preparation to treat these conditions.

Alpha-lipoic acid has also been used to treat rheumatoid arthritis, Alzheimer's disease, alcoholic liver problems, altitude sickness, heart-related nerve problems, HIV-related brain problems, or eye problems caused by diabetes. However, research has shown that alpha-lipoic acid may not be effective in treating these conditions.

Other uses not proven with research have included treating glaucoma, migraine headaches, high blood pressure, heart failure, dementia, carpal tunnel syndrome, leg pain caused by sciatic nerve damage or peripheral artery disease (PAD), anti-aging of the skin, and other conditions.

It is not certain whether alpha-lipoic acid is effective in treating any medical condition. Medicinal use of this product has not been approved by the FDA. Alpha-lipoic acid should not be used in place of medication prescribed for you by your doctor.

Alpha-lipoic acid is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Alpha-lipoic acid may also be used for purposes not listed in this product guide.

• Generic Name: dextran, low molecular weight
• Dosage Forms: n.a.
• Other Brand Names: LMD

Early fluid replacement and plasma volume expansion in the adjunctive treatment of certain types of shock or impending shock (e.g., burns, surgery, hemorrhage, or other trauma in which a circulating volume deficit is present) when whole blood or blood products are not available, or when the need for haste precludes the necessary cross-matching of blood.

Minimizes sludging of blood as a result of microcirculation effects.

Not a replacement for other forms of therapy; complementary to fluids and electrolytes.

Priming fluid (alone or as an additive to other priming fluids) in pump oxygenators for perfusion during extracorporeal circulation.

Prophylaxis of venous thrombosis and pulmonary embolism for surgical procedures associated with a high risk of thromboembolic complications (e.g., hip surgery).

May be beneficial in patients undergoing hip surgery; however, has not been shown to be more effective than oral anticoagulants or heparin in patients undergoing general surgery.

The American College of Chest Physicians (ACCP) does not recommend as sole method of thromboprophylaxis in elective hip arthroplasty.