Alphanine SD and Thiotepa Injection

• Generic Name: coagulation factor ix
• Dosage Forms: injection, powder, lyophilized, for solution
• Other Brand Names: Alphanine SD, Alprolix, BeneFIX, Idelvion, Ixinity, Mononine, Rebinyn, Rixubis, BeneFIX 250 Int'l Units, BeneFIX

Alphanine SD is a man-made protein similar to a natural protein in the body that helps the blood to clot.

Alphanine SD is used to treat or prevent bleeding in people with hemophilia B. This medication is not for treating people with hemophilia A factor VIII deficiency.

Alphanine SD may also be used for purposes not listed in this medication guide.

• Generic Name: thiotepa
• Dosage Forms: n.a.
• Other Brand Names: Thioplex, Tepadina

Thiotepa injection is used to lower risk of graft rejection when used with other medicines (eg, high-dose busulfan, cyclophosphamide) as a preparative regimen for stem cell transplantation in children with class 3 beta-thalassemia. It is also used to treat cancer of the breast, ovary, and urinary bladder. Thiotepa is also used to treat malignant effusions (accumulation of fluid in the body cavity) caused by cancer.

Thiotepa belongs to the group of medicines called alkylating agents. It interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by thiotepa, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, like hair loss, may not be serious but may cause concern. Some effects do not occur for months or years after the medicine is used.

Thiotepa is to be given only by or under the immediate supervision of your doctor.