Alprazolam Tablets and Sinemet 250/25
Determining the interaction of Alprazolam Tablets and Sinemet 250/25 and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:ALPRAZolam can decrease the effects of levodopa in some people. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your Parkinson symptoms worsen. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Benzodiazepines may decrease the therapeutic effects of levodopa in patients with Parkinson's disease. The mechanism is unknown.
MANAGEMENT: Patients receiving this combination should be monitored for altered clinical response. The benzodiazepine should be discontinued if an interaction is suspected.
- Hunter KR, Stern GM, Laurence DR "Use of levodopa with other drugs." Lancet 2 (1970): 1283-5
- Yosselson-Superstine S, Lipman AG "Chlordiazepoxide interaction with levodopa." Ann Intern Med 96 (1982): 259-60
- Mackie L "Drug antagonism." Br Med J 2 (1971): 651
Generic Name: alprazolam
Brand name: Niravam, Xanax, Xanax XR, Alprazolam Intensol
Synonyms: Alprazolam, ALPRAZolam
Generic Name: carbidopa / levodopa
Brand name: Parcopa, Rytary, Sinemet, Sinemet CR, Duopa
Synonyms: Carbidopa and levodopa, Carbidopa and Levodopa
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Alprazolam Tablets-Sinemet CR
- Alprazolam Tablets-Sinemet CR 100/25
- Alprazolam Tablets-Sinemet CR 200/50
- Alprazolam Tablets-Sinequan
- Alprazolam Tablets-Sinequan (Doxepin Capsules)
- Alprazolam Tablets-Sinequan (Doxepin Oral Concentrate)
- Sinemet 250/25-Alprazolam XR
- Sinemet 250/25-Alprolix
- Sinemet 250/25-Alprolix Intravenous
- Sinemet 250/25-Alprostadil
- Sinemet 250/25-Alprostadil (Prostin VR)
- Sinemet 250/25-Alprostadil injectable and transurethral