Alteplase (Catheter Clearance) and Denosumab Subcutaneous

• Generic Name: alteplase
• Dosage Forms: n.a.
• Other Brand Names: Activase, Cathflo Activase

• It is used to clear blood clots out of catheters.
• It may be given to you for other reasons. Talk with the doctor.

• Generic Name: denosumab
• Dosage Forms: n.a.
• Other Brand Names: Prolia, Xgeva

Denosumab injection is used to treat osteoporosis (thinning of the bones) in women who have an increased risk for fractures after menopause, and osteoporosis in men. It is given when other medicines cannot be used or after other medicines did not work well. It is also used to treat osteoporosis in patients using steroid medicines for at least 6 months.

Denosumab injection is also used to treat bone loss in men with prostate cancer and women with breast cancer who are receiving cancer treatment.

It is used to prevent bone problems in patients with multiple myeloma and bone metastases (cancer that has spread) from tumors. Denosumab is also used to treat giant cell tumor of the bone that cannot be removed by surgery. Denosumab is also used to treat hypercalcemia of malignancy that has been treated with bisphosphonates (eg, alendronate, ibandronate, risedronate, Fosamax®) but did not work well.

Denosumab is to be given only by or under the supervision of your doctor.