Altocor and Jantoven

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using warfarin together with lovastatin may cause you to bleed more easily. You may need a dose adjustment based on your prothrombin time or International Normalized Ratio (INR). Call your doctor promptly if you have any unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Lovastatin may enhance the hypoprothrombinemic effects of warfarin. Clinically significant alterations in anticoagulation have been reported. The mechanism is unknown.

MANAGEMENT: Caution is recommended if any HMG-CoA reductase inhibitor is used concomitantly with any oral anticoagulant. Close clinical and laboratory monitoring for altered anticoagulant effect is recommended. Patients should be advised to promptly report any signs of bleeding to their physician, including pain, swelling, headache, dizziness, weakness, prolonged bleeding from cuts, increased menstrual flow, vaginal bleeding, nosebleeds, bleeding of gums from brushing, unusual bleeding or bruising, red or brown urine, or red or black stools. Preliminary studies have shown that pravastatin and cerivastatin do not affect the anticoagulant response to warfarin.

Altocor

Generic Name: lovastatin

Brand name: Altocor, Altoprev, Mevacor

Synonyms: n.a.

What is Altocor?

Jantoven

Generic Name: warfarin

Brand name: Coumadin, Jantoven

Synonyms: n.a.

What is Jantoven?