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Aluminum hydroxide and Ferriprox (Deferiprone Tablets)

Determining the interaction of Aluminum hydroxide and Ferriprox (Deferiprone Tablets) and the possibility of their joint administration.

Check result:
Aluminum hydroxide <> Ferriprox (Deferiprone Tablets)
Relevance: 28.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Deferiprone and aluminum hydroxide should not be taken orally at the same time. Products that contain aluminum, calcium, iron, magnesium, and/or other minerals may interfere with the absorption of deferiprone and reduce its effectiveness. You should take these medications at least four hours apart. Contact your doctor if your condition worsens. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Deferiprone has the potential to bind polyvalent cations such as aluminum, iron and zinc, which may reduce its effectiveness. However, concurrent use with foods, mineral supplements, or antacids that contain polyvalent cations has not been studied.

MANAGEMENT: A minimum 4-hour interval is recommended between the administration of deferiprone and mineral supplements or oral medications that contain antacids (e.g., didanosine buffered tablets or pediatric oral solution) or other polyvalent cations.

References
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  • "Product Information. Ferriprox (deferiprone)." ApoPharma USA Inc, Rockville, MD.
  • Cerner Multum, Inc. "Australian Product Information." O 0
Aluminum hydroxide

Generic Name: aluminum hydroxide

Brand name: Amphojel, Alu-Cap, Dialume, Alu-Tab, Alternagel, Aloh-Gel

Synonyms: n.a.

Ferriprox (Deferiprone Tablets)

Generic Name: deferiprone

Brand name: Ferriprox

Synonyms: Ferriprox

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.