Aluminum hydroxide and Prednisolone ODT
Determining the interaction of Aluminum hydroxide and Prednisolone ODT and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Antacids and agents with acid-neutralizing effects may impair the absorption of dexamethasone, prednisolone, prednisone, and other corticosteroids, although data from published studies are somewhat conflicting. The mechanism of interaction and clinical significance are unknown. No particular intervention is necessary during concomitant therapy with these agents, but clinicians should be aware of the potential for interaction.
- Naggar VF, Khalil SA, Gouda MW "Effect of concomitant administration of magnesium trisilicate on GI absorption of dexamethasone in humans." J Pharm Sci 67 (1978): 1029-30
- Tanner AR, Caffin JA, Halliday JW, Powell LW "Concurrent administration of antacids and prednisone: effect on serum levels of prednisolone." Br J Clin Pharmacol 7 (1979): 397-400
- Albin H, Vincon G, Demotes-Mainard F, et al "Effect of aluminium phosphate on the bioavailability of cimetidine and prednisolone." Eur J Clin Pharmacol 26 (1984): 271-3
Generic Name: aluminum hydroxide
Brand name: Amphojel, Alu-Cap, Dialume, Alu-Tab, Alternagel, Aloh-Gel
Synonyms: n.a.
Generic Name: prednisolone
Brand name: Flo-Pred, Millipred, Millipred DP, Orapred, Orapred ODT, Pediapred, Veripred 20, Prelone, Hydeltra-TBA, Hydeltrasol, Key-Pred, Cotolone, Depo-Predate, Predicort-50, Predalone 50, Predacort 50, Predate-50, Predaject-50, Pred-Ject-50, Key-Pred SP, Medicort, Predicort RP, Pri-Cortin 50, Predcor, Bubbli-Pred, AsmalPred Plus, Flo-Pred Oral Suspension
Synonyms: Prednisolone, PrednisoLONE (Systemic)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Aluminum hydroxide-Prednisolone ophthalmic
- Aluminum hydroxide-Prednisolone Ophthalmic Suspension
- Aluminum hydroxide-Prednisolone Oral Solution
- Aluminum hydroxide-Prednisolone Orally Disintegrating Tablets
- Aluminum hydroxide-Prednisolone Sodium Phosphate
- Aluminum hydroxide-Prednisolone Sodium Phosphate eent
- Prednisolone ODT-Aluminum Hydroxide and Magnesium Carbonate Chewable Tablets
- Prednisolone ODT-Aluminum Hydroxide and Magnesium Carbonate Suspension
- Prednisolone ODT-Aluminum Hydroxide and Magnesium Hydroxide Chewable Tablets
- Prednisolone ODT-Aluminum Hydroxide and Magnesium Hydroxide Suspension
- Prednisolone ODT-Aluminum Hydroxide and Magnesium Trisilicate
- Prednisolone ODT-Aluminum hydroxide, magnesium hydroxide, and simethicone