Aluminum hydroxide and Sucralfate
Determining the interaction of Aluminum hydroxide and Sucralfate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using sucralfate together with aluminum hydroxide can decrease the effects of sucralfate. Sucralfate and aluminum hydroxide doses should be separated by at least half an hour. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSING INTERVAL: Antacid-induced gastric pH changes may reduce binding of sucralfate with the gastrointestinal mucosa resulting in reduced therapeutic efficacy. In addition, aluminum may accumulate in patients with renal failure who are concomitantly taking sucralfate with aluminum-containing antacids.
MANAGEMENT: Sucralfate and antacid doses should be separated by at least half an hour.
- "Product Information. Carafate (sucralfate)." Hoechst Marion-Roussel Inc, Kansas City, MO.
Generic Name: aluminum hydroxide
Brand name: Amphojel, Alu-Cap, Dialume, Alu-Tab, Alternagel, Aloh-Gel
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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