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Aluminum Hydroxide and Magnesium Carbonate Chewable Tablets and Macrodantin

Determining the interaction of Aluminum Hydroxide and Magnesium Carbonate Chewable Tablets and Macrodantin and the possibility of their joint administration.

Check result:
Aluminum Hydroxide and Magnesium Carbonate Chewable Tablets <> Macrodantin
Relevance: 15.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

The absorption of nitrofurantoin may be inhibited by magnesium-containing antacids. If a magnesium-containing product must be taken, administration of these agents should be separated by 2 to 3 hours.

References
  • Naggar VF, Khalil SA "Effect of magnesium trisilicate on nitrofurantoin absorption." Clin Pharmacol Ther 25 (1979): 857-63
Aluminum Hydroxide and Magnesium Carbonate Chewable Tablets

Generic Name: aluminum hydroxide / magnesium carbonate

Brand name: Gaviscon Extra Relief Formula, Acid Gone, Gaviscon

Synonyms: n.a.

Macrodantin

Generic Name: nitrofurantoin

Brand name: Furadantin, Macrobid, Macrodantin, Nitro Macro

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.