Aluminum Hydroxide and Magnesium Carbonate Suspension and Ibandronate
Determining the interaction of Aluminum Hydroxide and Magnesium Carbonate Suspension and Ibandronate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Ibandronate and aluminum hydroxide should not be taken orally at the same time. Products that contain magnesium, aluminum, calcium, iron, and/or other minerals may interfere with the absorption of ibandronate into the bloodstream and reduce its effectiveness. You should take aluminum hydroxide at least 30 minutes after the ibandronate dose. Talk to a healthcare professional if you are not sure whether a product contains something that could potentially interact with your medication or if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:ADJUST DOSING INTERVAL: Products containing aluminum, calcium, magnesium and other polyvalent cations such as antacids or vitamin with mineral supplements are likely to interfere with the gastrointestinal absorption of oral bisphosphonates. For example, the bioavailability of tiludronate has been shown to decrease 80% during simultaneous administration with calcium, and 60% when aluminum- or magnesium-containing antacids were administered one hour before tiludronate.
MANAGEMENT: Antacids or other oral medications containing aluminum, calcium, magnesium and other polyvalent cations should be administered at least 30 minutes after the bisphosphonate dose.
- Darcy PF "Nutrient-drug interactions." Adverse Drug React Toxicol Rev 14 (1995): 233-54
- "Product Information. Boniva (ibandronate)." Roche Laboratories, Nutley, NJ.
- "Product Information. Skelid (tilundronate)." Sanofi Winthrop Pharmaceuticals, New York, NY.
- "Product Information. Bonefos (clodronate)." Rhone-Poulenc Rorer Canada Inc, Laval, QC.
- "Product Information. Actonel (risedronate)." Procter and Gamble Pharmaceuticals, Cincinnati, OH.
- "Product Information. Fosamax (alendronate)." Merck & Co, Inc, West Point, PA.
Generic Name: aluminum hydroxide / magnesium carbonate
Brand name: Gaviscon Extra Relief Formula, Acid Gone, Gaviscon
Synonyms: Aluminum Hydroxide and Magnesium Carbonate Chewable Tablets
Generic Name: ibandronate
Brand name: Boniva, Bondronat
Synonyms: Ibandronate (oral/injection)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Aluminum Hydroxide and Magnesium Carbonate Suspension-Ibandronate Injection
- Aluminum Hydroxide and Magnesium Carbonate Suspension-Ibandronate Intravenous
- Aluminum Hydroxide and Magnesium Carbonate Suspension-Ibandronate oral/injection
- Aluminum Hydroxide and Magnesium Carbonate Suspension-Ibandronate Sodium
- Aluminum Hydroxide and Magnesium Carbonate Suspension-Ibandronate Sodium Injection
- Aluminum Hydroxide and Magnesium Carbonate Suspension-Ibandronate Sodium Tablets
- Ibandronate-Aluminum Hydroxide and Magnesium Hydroxide Chewable Tablets
- Ibandronate-Aluminum Hydroxide and Magnesium Hydroxide Suspension
- Ibandronate-Aluminum Hydroxide and Magnesium Trisilicate
- Ibandronate-Aluminum hydroxide, magnesium hydroxide, and simethicone
- Ibandronate-Aluminum Hydroxide, Magnesium Hydroxide, and Simethicone Chewable Tablets
- Ibandronate-Aluminum Hydroxide, Magnesium Hydroxide, and Simethicone Suspension