Aluminum Hydroxide and Magnesium Hydroxide Suspension and Calcitrate

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Ask your doctor before using aluminum hydroxide together with calcium citrate. Using these medications together can increase the effects of aluminum hydroxide which could result in too high of aluminum blood levels. If you have end-stage renal disease you are particularly at risk of developing high aluminum blood levels and encephalopathy (brain disease). You should separate doses of aluminum hydroxideand calcium citrate by 2 to 3 hours. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: The concomitant administration of aluminum-containing products (e.g., antacids and phosphate binders) and citrates may significantly increase serum aluminum concentrations, resulting in toxicity. Citrates enhance the gastrointestinal absorption of aluminum by an unknown mechanism, which may involve the formation of a soluble aluminum-citrate complex. Various studies have reported that citrate increases aluminum absorption by 4.6- to 50-fold in healthy subjects. Patients with end-stage renal disease are particularly at risk of developing hyperaluminemia and encephalopathy. Fatalities have been reported.

MANAGEMENT: The concomitant use of aluminum- and citrate-containing products should be avoided in renally impaired patients. Some experts also recommend that healthy patients should separate doses of aluminum-containing antacids and citrates by 2 to 3 hours.

Aluminum Hydroxide and Magnesium Hydroxide Suspension

Generic Name: aluminum hydroxide / magnesium hydroxide

Brand name: Alamag

Synonyms: Aluminum Hydroxide and Magnesium Hydroxide Chewable Tablets

What is Aluminum Hydroxide and Magnesium Hydroxide Suspension?

Calcitrate

Generic Name: calcium citrate

Brand name: Calcitrate, Citracal, Cit Calcium, Citracal Liquitab

Synonyms: n.a.

What is Calcitrate?