Aluminum Hydroxide and Magnesium Trisilicate and Dolobid
Determining the interaction of Aluminum Hydroxide and Magnesium Trisilicate and Dolobid and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Concomitant administration of diflunisal and aluminum-containing products reduces the oral bioavailability of diflunisal by up to 40%. Doses of diflunisal and aluminum-containing products should be separated by at least 2 hours to ensure adequate absorption of diflunisal. Patients should be monitored for altered clinical effects of diflunisal.
- "Product Information. Dolobid (diflunisal)." Merck & Co, Inc, West Point, PA.
- D'Arcy PF, McElnay JC "Drug-antacid interactions: assessment of clinical importance." Drug Intell Clin Pharm 21 (1987): 607-17
- Verbeeck R, Tjandramaga TB, Mullie A, Verbesselt R, de Schepper PJ "Effect of aluminum hydroxide on diflunisal absorption." Br J Clin Pharmacol 7 (1979): 519-22
Generic Name: aluminum hydroxide / magnesium trisilicate
Brand name: Drysol, Hypercare, Xerac AC, Gaviscon Tablet
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Aluminum Hydroxide and Magnesium Trisilicate-Dologen
- Aluminum Hydroxide and Magnesium Trisilicate-Dologesic
- Aluminum Hydroxide and Magnesium Trisilicate-Dologesic DF
- Aluminum Hydroxide and Magnesium Trisilicate-Dolono
- Aluminum Hydroxide and Magnesium Trisilicate-Dolophine
- Aluminum Hydroxide and Magnesium Trisilicate-Dolor-Parche with Lidocaine
- Dolobid-Aluminum hydroxide, magnesium hydroxide, and simethicone
- Dolobid-Aluminum Hydroxide, Magnesium Hydroxide, and Simethicone Chewable Tablets
- Dolobid-Aluminum Hydroxide, Magnesium Hydroxide, and Simethicone Suspension
- Dolobid-Alunbrig
- Dolobid-Alupent
- Dolobid-Alupent (Metaproterenol Syrup)