Aluminum Hydroxide and Magnesium Trisilicate and Hydrocortisone Enema
Determining the interaction of Aluminum Hydroxide and Magnesium Trisilicate and Hydrocortisone Enema and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Antacids and agents with acid-neutralizing effects may impair the absorption of dexamethasone, prednisolone, prednisone, and other corticosteroids, although data from published studies are somewhat conflicting. The mechanism of interaction and clinical significance are unknown. No particular intervention is necessary during concomitant therapy with these agents, but clinicians should be aware of the potential for interaction.
- Naggar VF, Khalil SA, Gouda MW "Effect of concomitant administration of magnesium trisilicate on GI absorption of dexamethasone in humans." J Pharm Sci 67 (1978): 1029-30
- Tanner AR, Caffin JA, Halliday JW, Powell LW "Concurrent administration of antacids and prednisone: effect on serum levels of prednisolone." Br J Clin Pharmacol 7 (1979): 397-400
- Albin H, Vincon G, Demotes-Mainard F, et al "Effect of aluminium phosphate on the bioavailability of cimetidine and prednisolone." Eur J Clin Pharmacol 26 (1984): 271-3
Generic Name: aluminum hydroxide / magnesium trisilicate
Brand name: Drysol, Hypercare, Xerac AC, Gaviscon Tablet
Synonyms: n.a.
Generic Name: hydrocortisone
Brand name: Cortef, Colocort, Cortenema, Cortifoam, Solu-Cortef
Synonyms: Hydrocortisone, Hydrocortisone (Systemic)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Aluminum Hydroxide and Magnesium Trisilicate-Hydrocortisone in Absorbase
- Aluminum Hydroxide and Magnesium Trisilicate-Hydrocortisone injection
- Aluminum Hydroxide and Magnesium Trisilicate-Hydrocortisone Injection Solution
- Aluminum Hydroxide and Magnesium Trisilicate-Hydrocortisone Iodoquinol Cream
- Aluminum Hydroxide and Magnesium Trisilicate-Hydrocortisone Lotion
- Aluminum Hydroxide and Magnesium Trisilicate-Hydrocortisone Lotion and Protective Emollient Cream
- Hydrocortisone Enema-Aluminum hydroxide, magnesium hydroxide, and simethicone
- Hydrocortisone Enema-Aluminum Hydroxide, Magnesium Hydroxide, and Simethicone Chewable Tablets
- Hydrocortisone Enema-Aluminum Hydroxide, Magnesium Hydroxide, and Simethicone Suspension
- Hydrocortisone Enema-Alunbrig
- Hydrocortisone Enema-Alupent
- Hydrocortisone Enema-Alupent (Metaproterenol Syrup)