Ambien CR and Flumazenil
Determining the interaction of Ambien CR and Flumazenil and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:A case report has suggested that flumazenil may reverse coma and respiratory depression in patients experiencing zolpidem toxicity. Also, a small study has confirmed that flumazenil antagonizes the central effects of zolpidem and has suggested that the interaction may be attributable to pharmacodynamic effects.
- Patat A, Naef MM, Vangessel E, Forster A, Dubruc C, Rosenzweig P "Flumazenil antagonizes the central effects of zolpidem, an imidazopyridine hypnotic." Clin Pharmacol Ther 56 (1994): 430-6
- Lheureux P, Debailleul G, De Witte O, Askenasi R "Zolpidem intoxication mimicking narcotic overdose: response to flumazenil." Hum Exp Toxicol 9 (1990): 105-7
Generic Name: zolpidem
Brand name: Ambien CR, Ambien, Edluar, Intermezzo, ZolpiMist
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Ambien CR-Flumazenil Injection
- Ambien CR-Flumist
- Ambien CR-FluMist 2018-2019 nasal
- Ambien CR-FluMist Quadrivalent
- Ambien CR-FluMist Quadrivalent 2015-2016 Formula
- Ambien CR-Flunisolide
- Flumazenil-Ambien CR Oral
- Flumazenil-Ambien Oral
- Flumazenil-Ambifed CD
- Flumazenil-Ambifed-G
- Flumazenil-Ambisome
- Flumazenil-Ambrisentan