Ambrisentan Tablets and Atazanavir and cobicistat
Determining the interaction of Ambrisentan Tablets and Atazanavir and cobicistat and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Based on in vitro data, coadministration with potent inhibitors of CYP450 3A4 and/or 2C19 may be expected to increase the plasma concentrations of ambrisentan, which is a substrate of these isoenzymes. However, administration with ketoconazole (potent CYP450 3A4 inhibitor) or omeprazole (potent CYP450 2C19 inhibitor) did not result in clinically relevant changes in ambrisentan exposure.
- "Product Information. Letairis (ambrisentan)." Gilead Sciences, Foster City, CA.
Generic Name: ambrisentan
Brand name: Letairis
Synonyms: Ambrisentan
Generic Name: atazanavir / cobicistat
Brand name: Evotaz
Synonyms: Atazanavir and Cobicistat
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Ambrisentan Tablets-Atazanavir Capsules
- Ambrisentan Tablets-Atazanavir Powder for Oral Suspension
- Ambrisentan Tablets-Atazanavir Sulfate
- Ambrisentan Tablets-Atelvia
- Ambrisentan Tablets-Atendia Patch
- Ambrisentan Tablets-Atenolol
- Atazanavir and cobicistat-Amcinonide
- Atazanavir and cobicistat-Amcinonide Cream and Ointment
- Atazanavir and cobicistat-Amcinonide Lotion
- Atazanavir and cobicistat-Amcinonide Ointment
- Atazanavir and cobicistat-Amcinonide topical
- Atazanavir and cobicistat-Amcinonide Topical application