Ambrisentan Tablets and Posaconazole Oral Suspension
Determining the interaction of Ambrisentan Tablets and Posaconazole Oral Suspension and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Based on in vitro data, coadministration with potent inhibitors of CYP450 3A4 and/or 2C19 may be expected to increase the plasma concentrations of ambrisentan, which is a substrate of these isoenzymes. However, administration with ketoconazole (potent CYP450 3A4 inhibitor) or omeprazole (potent CYP450 2C19 inhibitor) did not result in clinically relevant changes in ambrisentan exposure.
- "Product Information. Letairis (ambrisentan)." Gilead Sciences, Foster City, CA.
Generic Name: ambrisentan
Brand name: Letairis
Synonyms: Ambrisentan
Generic Name: posaconazole
Brand name: Noxafil
Synonyms: Posaconazole (oral/injection), Posaconazole
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Ambrisentan Tablets-Posaconazole oral/injection
- Ambrisentan Tablets-Posaconazole Tablets
- Ambrisentan Tablets-PosiFlush flush
- Ambrisentan Tablets-Positive Skin Test Control - Histamine
- Ambrisentan Tablets-Posture
- Ambrisentan Tablets-Potaba
- Posaconazole Oral Suspension-Amcinonide
- Posaconazole Oral Suspension-Amcinonide Cream and Ointment
- Posaconazole Oral Suspension-Amcinonide Lotion
- Posaconazole Oral Suspension-Amcinonide Ointment
- Posaconazole Oral Suspension-Amcinonide topical
- Posaconazole Oral Suspension-Amcinonide Topical application